Clinical case of a female patient with sarcoidosis and anterior nasal septum perforation
Medical Review (Med. pregled), 2024, 60(4), 63-66.
R. Gancheva1, A. Koundurdjiev2, I. Koundurdjieva3, L. Marinchev1
1 Clinic of Rheumatology, University Hospital “Sofiamed”, Sofia University „Sv. Kliment Ohridski“
2 Clinic of Nephrology, University Hospital “Sv. Iv. Rilski”, Medical University – Sofia;
3 Clinic of Otorhinolaryngology, University Hospital Freiburg
Abstract. Sarcoidosis is a chronic multisystemic granulomatous disease of unknown etiology. Rarely, it can affect the nose and the paranasal sinuses, leading to the development of nasal polyposis, epistaxis, recurrent sinusitis, hypoosmia/anosmia, nasal septum perforation and saddle nose deformity. The authors present a 46-years-old female patient admitted in rheumatology clinic for diagnostic evaluation of lowgrade fever, in the evening, diffuse joint pain, productive cough, bloody rhinorrhea, and anosmia that progressed over the past two years. A month before the admission the patient developed perforation of the anterior and middle third of the nasal septum. Immunological studies ruled out ANCA-associated vasculitis and the histopathological examination of the lesion revealed sarcoidosis. The patient was started on corticosteroids. The authors present the current knowledge on the treatment of sarcoidosis involving the nasal septum.
Key words: sarcoidosis, nasal septum perforation, anosmia
Address for correspondence: Rada Gancheva, MD, PhD, e-mail: rada_ga@mail.bg