Troponin as a laboratory biomarker for cardiovascular diseases
General Medicine, 2025, 27(2), 54-60.
M. Atanasova, K. Ikonomova
Clinical Laboratory and Immunology, National Multiprofile Transport Hospital – Sofia
Abstract. Laboratory biomarkers have become an important tool for assessing the risk of cardiovascular diseases. Laboratory biomarkers have become an important tool for assessing the risk of cardiovascular diseases. They provide information about the course of pathological processes and help predict future complications. The heart-specific biomarker troponin is widely used in clinical practice. Its physiological role, its variation depending on some biological factors, and its participation in the pathophysiology of cardiovascular diseases are presented. The study of high-sensitivity troponin (hsTn) has expanded the possibilities for earlier diagnosis of cardiac damage. Attention is paid to some specific laboratory problems related to the research methods and the modern equipment used in their study. The role of hsTn in risk assessment, diagnosis, and monitoring of cardiovascular diseases is considered.
Key words: high-sensitivity troponins – biological and analytical variations, biomarker for risk assessment, diagnosis and monitoring of cardiovascular diseases