Eosinophilic ascites – casе report and literature review

General Medicine, 2023, 25(4), 51-55.

S. Bezhanova1, S. Dineva2 S. Marina3

1 Clinic of Gastroenterology, Medical Institute, Ministry of the Interior ‒ Sofia
2 Clinic of Medical imaging, Medical Institute, Ministry of the Interior ‒ Sofia
3 Clinic of Dermatology, Medical Institute, Ministry of the Interior ‒ Sofia

Abstract. Background: Eosinophilic ascites is the most unusual presentation of eosinophilic gastroenteritis (EGE), caused by edema and eosinophilic inflammation of the small bowel wall’s serosal layer. Case Report: We report the case of a 53-year-old man, who presented with abdominal pain and distension, moderate ascites since two-three weeks. Ultrasound, CT and Magnetic Resonance Imaging (MRI) showed the presence of ascites and diffuse thickening of small bowel wall, no malignancy in the abdominal cavity or signs of portal hypertension or liver damage. Laboratory test results revealed essential peripheral blood eosinophilia, elevated CRP and increase of eosinophils in the abdominal fluid. Treatment with corticosteroids and antihistamines normalized laboratory tests results, and the ascites resolved for about a week. Conclusions: EGE is a rare disease and it should be kept in mind in patients of unexplained ascites. The absence of primary malignancy on imaging, marked increase of peritoneal fluid eosinophilia and immediate response to treatment with steroids, confirm indirectly the diagnosis of EGE.

Key words: Eosinophilic gastroenteritis, Eosinophilic ascites, Eosinophilia

Address for correspondence: Svetlana Bezhanova, е-mail: svetla_beganova@abv.bg