Nomograms for measurements of length to width ratio of cavum septi pellucidi

Bulgarian Medical Journal, 16, 2022,№ 3, 42-46.

I. Markova1, P. Markov2, B. Terziyski3

1 MC “Trinity” ‒ Sofia; South-West University “Neofit Rilski” ‒ Blagoevgrad
2 MC “Trinity” ‒ Sofia; Аcibadem City Clinic Tokuda Hospital ‒ Sofia
3 “Maichin dom” Hospital ‒ Sofia

Abstract. Objective: The aim of the study was to propose nomograms for the cavum septi pellucidi (CSP) dimensions of the Bulgarian population in two week intervals for those gestational weeks when CSP can be visualized (16-37 + 6 w.g), to calculate the ratio between the length and width of CSP (CSP ratio) and to determine their relationship with the biparietal diameter (BPD) of the fetus. Material and methods: A prospective study was performed from October 2019 to October 2021. The measurements of length and width of CSP were performed in the transthalamic plane as for the BPD measurements. A total of 742 fetuses with normal fetal anatomy between 16 and 38 weeks of gestation were enlisted in the study. CSP measurement was taken in every fetus and the CSP ratio was calculated. The median value for CSP ratio was determined in every group, as well as calculations for standard deviations (SD) ranging between -2SD to +2SD. The relationship with fetal BPD was also evaluated. Results: CSP ratio rises progressively from 16 to 24 w.g. Afterwards, the ratio remains almost the same with small deviations till 37+6 w.g. There is a direct correlation between the rise in BPD and the rise in the dimensions of CSP. Conclusions: The current study provides nomograms of the CSP ratio for the Bulgarian population, which is an indicator for normal development of the fetal brain structures.

Key words: cavum septi pellucidi, nomogram, length to wide ratio

Address for correspondence: Irina Markova, MD, е-mail: dr_rinna@abv.bg