The infections as a cause of Guillain-Barre syndrome
Medical Review (Med. pregled), 2026, 62(2), 5-11.
А. Gotseva1, T. Valkov2
1Laboratory of Virology, Military Medical Academy – Sofia
2Faculty of Medicine, Medical University – Sofia
3Department of Infectious Diseases, “Prof. Ivan Kirov” Hospital – Sofia
Abstract: Guillain-Barre syndrome (GBS) is a rare autoimmune disease, characterized by a rapidly progressive ascending paralysis and involvement of peripheral nerves. The most common subtypes of GBS are acute inflammatory demyelinating poly-radiculoneuropathy and acute motor axonal neuropathy. GBS typically develops after a previous gastrointestinal or respiratory infection. Various viral and bacterial pathogens have been identified as triggers of GBS. The most common infectious agents linked to GBS include Campylobacter jejuni, Mycoplasma pneumoniae, Hepatitis E virus, Cytomegalovirus, Epstein-Barr virus, and Zika virus. GBS can be potentially life-threatening condition. Most people achieve a full recovery.
Key words: Guillain-Barré syndrome, antiganglioside antibodies, infection
Address for correspondence: Assoc. Prof. Aneliya Gotseva, MD, PhD, e-mail: anelialg@abv.bg