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Importance of some clinical factors (epilepsy duration, clusters of seizures and/or epileptic status, type of epilepsy, type of seizures, mono-/polytherapy) for the quality of life of patients with refractory epilepsy

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dc.contributor.author Viteva, E.
dc.date.accessioned 2014-07-10T13:38:51Z
dc.date.available 2014-07-10T13:38:51Z
dc.date.issued 2012-06
dc.identifier.citation E. Viteva. Importance of some clinical factors (epilepsy duration, clusters of seizures and/or epileptic status, type of epilepsy, type of seizures, mono-/polytherapy) for the quality of life of patients with refractory epilepsy - Acta medica bulgarica , 39, 2012, No 2, 89-96. en_US
dc.identifier.issn 0324-1750
dc.identifier.uri http://hdl.handle.net/10861/549
dc.description Address for correspondence: Dr. Ekaterina Viteva, Ph.D.; Medical University of Plovdiv; Department of Neurology; 15A Vasil Aprilov str.; 4002 Plovdiv, Bulgaria; tel.: +359887752235; e-mail: kiv14477@yahoo.com en_US
dc.description.abstract To assess the impact of the duration of epilepsy, the clusters of seizures and/or epileptic status, the type of epilepsy and seizures, and the mono-/ polytherapy on the quality of life (QOL) of Bulgarian patients with refractory epilepsy (RE). Seventy patients with RE were studied using a purposeful interview on the patients’ disease course, as well as an exam of the patients’ medical documentation. All study participants completed QOLIE-89. The greater duration of epilepsy has a negative impact on the assessments of the change in health during the last year. Seizure clusters and/or epileptic status in the disease course are associated with lower assessments of the sexual relations. The type of epilepsy has an impact on: 1. Seizure worries – participants with generalized epilepsy have less worries; 2. The overall score of QOLIE-89 – the patients with partial epilepsy make lower assessments. An impact of the seizure type on the subscale “Overall health” has been demonstrated. The lowest scores are given by the patients having partial seizures with secondary generalization. The highest scores are given by the participants having generalized tonic-clonic seizures, generalized myoclonic seizures, and polymorphic seizures. The prescribed treatment as mono-/polytherapy has an impact on the assessments of the overall health − the scores were higher in cases with polytherapy. The clinical factors duration of epilepsy, clusters of seizures and/ or epileptic status, type of epilepsy, type of seizures, mono-/polytherapy have an impact on single aspects of the QOL of the patients with RE. en_US
dc.language.iso en en_US
dc.publisher Централна медицинска библиотека, МУ София / Central Medical Library - MU Sofia en_US
dc.subject quality of life, refractory epilepsy, duration, mono-/polytherapy, seizure clusters, epileptic status en_US
dc.title Importance of some clinical factors (epilepsy duration, clusters of seizures and/or epileptic status, type of epilepsy, type of seizures, mono-/polytherapy) for the quality of life of patients with refractory epilepsy en_US
dc.type Article en_US


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  • Acta Medica Bulgarica
    Многопрофилно списание, излизащо само на английски език. Съдържа авторски статии от водещи български медицински специалисти, отразяващи върховите постижения на българската медицина наука и практика. Публикуват се материали, отразяващи резултати от експериментални проучвания, клиника и казуистика. Излиза 2 пъти годишно. ISSN:0324-1750

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