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Mesangial lipoidosis with cholesterol deposition – a new case with nephrotic syndrome and rapidly progressing renal failure

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dc.contributor.author Robeva, R.
dc.contributor.author Todorov, T.
dc.contributor.author Dimitrova, V.
dc.contributor.author Yordanov, M.
dc.contributor.author Doychinov, D.
dc.date.accessioned 2014-02-07T10:53:19Z
dc.date.available 2014-02-07T10:53:19Z
dc.date.issued 2011-10
dc.identifier.citation R. Robeva, T. Todorov, V. Dimitrova, M. Yordanov and D. Doychinov. Mesangial lipoidosis with cholesterol deposition – a new case with nephrotic syndrome and rapidly progressing renal failure - Acta medica bulgarica , 38, 2011, No 2, 62-66. en_US
dc.identifier.issn 0324-1750
dc.identifier.uri http://hdl.handle.net/10861/430
dc.description Address for correspondence: Assoc. Prof. R. Robeva, MD; Univ. Hosp. ”St . Ivan Rilski”; Dialysis and Clinical Pharmacology; 15, Blvd.” Acad. Ivan Geshov”; 1431 Sofia; tel. +35928510846 en_US
dc.description.abstract More than 140 years ago, fi rst Virchow associated observed lipid abnormalities with the concomitant renal disease. Despite a large body of clinical and laboratory evidence, the precise role of the lipids in the development of the renal disease remains unclear. In 1988, D. Doychinov described a new autosomal dominant hereditary disease leading to cholesterol accumulation within the glomerular mesangium. We report the case of a young man (a member of the affected family) with the same biopsy proven disease but with different clinical abnormalities and course. This patient had an overt nephrotic syndrome from the onset: 5 g/24h proteinuria, hypoproteinemia (52 g/l), hypoalbuminemia (28 g/l), hypercholesterolemia (8.5 mmol/l), edema as well as severe hypertension (180-200/110-120 mm Hg). Five years later he developed renal failure and after another three he was put on hemodialysis. en_US
dc.language.iso en en_US
dc.publisher Централна медицинска библиотека, МУ София / Central Medical Library - MU Sofia en_US
dc.subject mesangial lipoidosis, nephrotic syndrome, renal insuffi ciency en_US
dc.title Mesangial lipoidosis with cholesterol deposition – a new case with nephrotic syndrome and rapidly progressing renal failure en_US
dc.type Article en_US


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  • Acta Medica Bulgarica
    Многопрофилно списание, излизащо само на английски език. Съдържа авторски статии от водещи български медицински специалисти, отразяващи върховите постижения на българската медицина наука и практика. Публикуват се материали, отразяващи резултати от експериментални проучвания, клиника и казуистика. Излиза 2 пъти годишно. ISSN:0324-1750

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